Three distinct directions of intramural activation reveal non-uniform side-to-side electrical coupling of ventricular myocytes Short Title: Orthotropic Intramural Spread of LV Activation

نویسندگان

  • Bryan J Caldwell
  • Mark L Trew
  • Gregory B Sands
  • Darren A Hooks
  • Ian J LeGrice
  • Bruce H Smaill
  • Bruce H. Smaill
چکیده

A A A A A Auc uc uc uc uc uc uckl kl kl kl k k k an an an an an an and, d, d d d d d N N N N N N New ew ew ew ew ew ew ences es es es es es es Un Un Un Un Un Un Univ iv iv iv iv iv iver er er er er er ersi s s s s t y gy y t ssoc ate o esso o ys o ogy y gy y New Zealand ABSTRACT Background: The anisotropy of cardiac tissue is a key determinant of 3D electrical propagation

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Three distinct directions of intramural activation reveal nonuniform side-to-side electrical coupling of ventricular myocytes.

BACKGROUND The anisotropy of cardiac tissue is a key determinant of 3D electric propagation and the stability of activation wave fronts in the heart. The electric properties of ventricular myocardium are widely assumed to be axially anisotropic, with activation propagating most rapidly in the myofiber direction and at uniform velocity transverse to this. We present new experimental evidence tha...

متن کامل

Laminar arrangement of ventricular myocytes influences electrical behavior of the heart.

The response of the heart to electrical shock, electrical propagation in sinus rhythm, and the spatiotemporal dynamics of ventricular fibrillation all depend critically on the electrical anisotropy of cardiac tissue. A long-held view of cardiac electrical anisotropy is that electrical conductivity is greatest along the myocyte axis allowing most rapid propagation of electrical activation in thi...

متن کامل

Ortner’s Syndrome-A Rare Cause of Hoarseness: Its Importance to an Otorhinolaryngologist

Introduction: Cardiovocal hoarseness (Ortner’s syndrome) is hoarseness of voice due to recurrent laryngeal nerve involvement secondary to cardiovascular disease. Recurrent laryngeal nerve in its course (especially the left side) follows a path that brings it in close proximity to numerous structures. These structures interfere with its function by pressure or by disruption of the nerve caused b...

متن کامل

Cardiac structure and electrical activation: models and measurement.

1. Our group has developed finite element models of ventricular anatomy that incorporate detailed structural information. These have been used to study normal electrical activation and re-entrant arrhythmia. 2. A model based on the actual three-dimensional microstructure of a transmural left ventricular (LV) segment predicts that cleavage planes between muscle layers may give rise to non-unifor...

متن کامل

Left ventricular phosphorylation patterns of Akt and ERK1/2 after triiodothyronine intracoronary perfusion in isolated hearts and short-term in vivo treatment in Wistar rats

Objective(s): To determine the effects of triiodothyronine (T3) intracoronary perfusion in isolated hearts and short-term administration in rats on the left ventricular (LV) phosphorylation patterns of Akt and ERK1/2. Materials and Methods: Cardiodynamic and hemodynamic parameters were evaluated in Langendorff–perfused hearts. Left ventr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009